We are seeking a Research Specialist that is a driven individual to join a laboratory that uses mouse models of bone marrow transplantation (BMT) to study the epigenetic mechanisms contributing to the development of graft-versus-host disease (GVHD) and the graft-versus-leukemia (GVL) effect.

Specific Duties & Responsibilities

• Conduct murine BMT experiments using established protocols that include,
• Harvest of murine spleen for single cell suspension.
• Splenic T-cell purificatio.
• Splenic T-cell flow cytometry.
• Harvest of murine bone marrow.
• Animal irradiation.
• Tail vein injections.
• Participate in long-term monitoring of experiments, including examination of animals and GVHD scoring using an established clinical scale.
• Assist with analyzing and interpreting murine GVHD and survival data.
• Participate in post-transplant analyses, including the procurement of organs for fixation, and single-cell suspensions for surface and intracellular multiparameter flow cytometry staining of lymphoid and myeloid cells.
• Analyze and interpret flow cytometry data.
• Collaborate with the PI to oversee scientific management of the laboratory.
• Collaborate with PI or other lab members on research projects
• Identify and select best options for scientific strategies and research development based on literature reviews and collaboration with colleagues.
• Perform a range of laboratory assays.
• Contribute to writing of scientific publications and grant applications.
• Act as a resource for laboratory techniques for post-doctoral fellow and students and junior technicians.

• Bachelor's Degree in Biology, Chemistry or related field.
• One year laboratory experience performing relevant techniques.
• Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.

Classified Title: Research Specialist 
Job Posting Title (Working Title): Research Specialist   
Role/Level/Range: ACRP/03/MA  
Starting Salary Range: $16.92 - $29.61 HRLY (Commensurate with experience) 
Employee group: Full Time 
Schedule: M-F, 830-500 
Exempt Status: Non-Exempt 
Location: School of Medicine - East Baltimore Campus 
Department name: 10002936-SOM Onc Pediatric Oncology 
Personnel area: School of Medicine