Job Description

Description of Duties:

Postdoc positions are available immediately, in Dr. Dean Tang’s laboratory (https://www.roswellpark.org/dean-tang), to study NIH grant-supported projects that are centered on understanding prostate cancer cell heterogeneity/plasticity (Li Q et al., Nat. Commun. 2018; Zhang D et al., Nat. Commun. 2020; Kirk J. et al., Cell Stem Cell 2024) and the mechanisms of action of tumor suppressor LRIG1 (Li Q, et al., Nat. Commun. 10:5494, 2019; Ji Y. et al., Semin. Cancer Biol. 2022). The main ongoing projects include, among others: 1) investigating the tumor-suppressive functions of LRIG1 in novel genetic mouse models; 2) uncovering the novel LRIG1-interacting protein partners in both androgen-dependent and androgen-independent prostate cancers; 3) developing LRIG1-based biomarkers and therapeutics; and 4) elucidating the epigenetic underpinnings of treatment-induced plasticity in prostate cancer cells.

Qualifications:

Potential candidates should have received solid Ph.D training in molecular biology and biochemistry as evidenced by high-quality peer-reviewed publications. Candidates with strong (prostate) cancer biology knowledge and working experience in genetically engineered mouse models (GEMMs) are strongly encouraged to apply and will be given priority considerations.

Salary:

Commensurate with relevant research experience and NIH pay scale

Applicant Instructions:

Suitable candidates should submit the NIH biosketch and/or full CV with the names of 3 referees to:

Dr. Dean Tang
Professor & Chair
Department of Pharmacology & Therapeutics
Roswell Park Comprehensive Cancer Center
Dean.Tang@RoswellPark.org

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